Most men who come to Dr. Shefketova’s clinic with unexplained infertility have had standard sperm tests. Count, motility, morphology — all normal. And yet conception is not happening.

Oxidative stress is often the missing answer.

What is oxidative stress and why does it matter?

Oxidative stress occurs when free radicals in the body outnumber its ability to neutralise them. In men, this imbalance damages sperm at a cellular level — affecting the membrane, the DNA, and the sperm’s ability to fertilise an egg.

The result can be:

— Reduced sperm motility
— DNA fragmentation
— Failed fertilisation despite normal sperm count
— Poor embryo development
— Recurrent pregnancy loss

This is not a rare condition. Clinical studies identify oxidative stress as one of the most commonly overlooked causes of male infertility — and one of the most treatable once identified.

How is it tested?

The MiOXSYS system measures Oxidation-Reduction Potential (ORP) directly in a semen sample. It gives Dr. Shefketova’s team a precise picture of oxidative stress severity — something a standard spermogram cannot show.

Higher ORP values indicate more severe oxidative stress and a clearer explanation for why conception has not occurred.

The test is quick, non-invasive and gives results that can change the entire direction of treatment.

What happens after the test?

If elevated oxidative stress is confirmed, a personalised treatment plan is developed. This may include targeted antioxidant therapy, lifestyle adjustments, and a referral to a urologist or andrologist where needed.

The goal is not just a test result. It is a clear path forward.

Many couples who have spent years trying to conceive — and years being told everything looks normal — find their first real answer here.

You deserve a real answer too.

Dr. Shefketova and her specialist team — including experienced embryologists — are with you at every step.

The Emotional Side of Male Fertility Testing

For many men, fertility testing is uncomfortable. It can feel isolating — especially when most of the focus in fertility treatment falls on women.

At Dr. Shefketova’s clinic, male fertility is taken as seriously as female fertility. Every couple is assessed as a unit. There is no judgement here — only clear information and a path forward.

You are not alone in this. And the first step is easier than you think.

Book an appointment with Dr. Shefketova’s team →