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Intracytoplasmic Sperm Injection (ICSI)

ICSI in Sofia – Dr. Meftune Shefketova applies advanced reproductive techniques to help couples overcome infertility through personalized and effective fertility care. ICSI involves the direct injection of a single sperm into the egg’s cytoplasm using specialized microscopic techniques. Only mature eggs can be fertilized with this method. Fertilization is assessed the following day.

ICSI is used for male factor infertility, such as:
- Low sperm count (oligospermia)
- Reduced motility (asthenospermia)
- Abnormal sperm morphology (teratospermia)
- Obstructive azoospermia (e.g., after vasectomy)
- High DNA fragmentation in sperm
- Failed previous fertilization attempts
For more information about ICSI, visit the European Society of Human Reproduction and Embryology (ESHRE)
Learn more about IVF treatment in Sofia and other fertility options provided by Dr. Shefketova.